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Pfizer cuts full-year outlook due to declining sales of Covid-19-related products_我的网站

一 |     Shares of Pfizer are in retreat on the first day of trading after the drug company said sales of its COVID-19 vaccine and its coronavirus treatment are weaker than it had expected and cut revenue projections by $9 billion for the year. Falling sales of both clipped sales in the second quarter, but Pfizer said in August that it expected a rebound in the second half of 2023. Shares of Pfizer slipped more than 1% before the opening bell Monday and Moderna, which is heavily reliant on the competing vaccine it makes, slid nearly 5%. Pfizer said Friday that global usage of Paxlovid is trending slightly above last year, but that it's still below expectations.The fall vaccination period just began and the New York City drugmaker said that it's too soon to get a handle on vaccination rates for the year.Full-year revenue for Paxlovid and Comirnaty is expected to be approximately $12.5 billion, short $9 billion of what it had expected. Pfizer is lowering its full-year revenue expectations for Paxlovid by approximately $7 billion. That number also accounts for delayed commercialization of the product, which was pushed to January 2024 from the company's previous expectation of commercialization in the second half of this year. Pfizer is also lowering its 2023 revenue expectations for Comirnaty by approximately $2 billion due to lower-than-expected vaccination rates.Pfizer Inc. now foresees 2023 revenue in a range of $58 billion to $61 billion, down from its prior forecast for $67 billion to $70 billion. It now projects full-year adjusted earnings between $1.45 and $1.65 per share due to lower-than-anticipated revenue for COVID-19-related products and inventory write-offs.That is short of the full-year revenue of $63.61 billion and earnings of $2.77 per share that Wall Street was expecting, and far short of the company's previous projections of per-share earning between $3.25 and $3.45. JPMorgan said the company's update solves an ongoing U.S. Paxlovid inventory debate and it anticipates the company's bigger-than-expected cuts to its sales projections will help put a floor under per-share earnings expectations for next year.。    (ECNS) -- A medical team in Shanxi Province on Wednesday performed the region's first invasive brain‑computer interface (BCI) implant surgery, opening up new possibilities for restoring mobility in patients with spinal cord injuries.    The surgery was performed by a team led by Guo Geng, director of the BCI Clinical Research Center at the First Hospital of Shanxi Medical University.    The system enables the patient, who has high-level paralysis for three years, to control external devices through brain signals including computers, smart home equipment.    It can also enable the control of a pneumatic glove to perform daily tasks such as drinking and eating, and may eventually help patients regain independent hand movement.    Stable collection, transmission, and decoding of neural signals have been observed since a flexible cortical electrode, measuring just 10 micrometers thick, was placed on the target brain area.    According to Guo, the system is designed for full internal implantation, which reduces infection risk and allows patients to use it more conveniently in everyday life. Its ultra-flexible electrodes capture brain signals while minimizing damage to surrounding tissue. The system also integrates wireless charging and Bluetooth data transmission, with a response delay as low as 50 milliseconds.    The surgery marks a milestone for invasive BCI research in Shanxi and provides new hope for millions of people with spinal cord injuries and paralysis.    (By Intern Liu Shuangjing, Zhang Dongfang)                    。

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