
一 | Researchers from the University of California's San Diego School of Medicine have found that gonorrhea, as unpleasant as it is, might be the reason that our grandparents even exist.,Humans are among the few species that continue to live after menopause, which might be because of the evolution-proven support that older women provide when it comes to raising children.,The new findings suggest that pressure from pathogens like gonorrhea developed human gene mutations that protected elderly people from cognitive decline and made sure they could live longer.,The discovery comes by comparing human and chimpanzee genomes. The comparison revealed that humans have their own unique version of the gene for CD33, a receptor in immune cells that plays an important role in binding to a type of sugar called sialic acid. Human cells are coated with it and it helps immune cells "recognize" other cells and not attack them.,"Somewhere along the evolutionary line, humans picked up an additional mutated form of CD33 that is missing the sugar-binding site," the authors said. "The mutated receptor no longer reacts to sialic acids on damaged cells and plaques, allowing the microglia to break them down. Indeed, higher levels of this CD33 variant were independently found to be protective against late-onset Alzheimer's.",It would seem that CD33 was selected by evolution for its survival advantages, later making sure that humans were able to have big families that represent several generations. All of this, albeit indirectly, thanks to gonorrhea.。

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三 | 今年5月底在巴黎举行的欧冠决赛,因赛前球迷入场的混乱造成比赛推迟36分钟才开哨,赛后当地警方和球迷的互相指责引人关注,这也进一步引发了人们对巴黎奥运会安保问题的担忧。

四 | 毕竟,相比一场足球赛,奥运会的时间跨度长得多,涉及的人员规模也要大得多。尤其是在塞纳河边这场计划由60万人参与的开幕式大派对,更成为所有人担心的焦点。就在倒计时两周年的前一天,法国总统马克龙召集多位有关部门的政府高级官员以及巴黎奥组委的负责人召开了一次线下会议,讨论的重点之一就是如何应对奥运期间的安全问题。

五 | 据法国媒体透露,法国政府甚至不排除最终会调动军队来维持开幕式现场的秩序,防止意外情况的发生。具体到赛事期间,法国政府有可能将推迟包括环法在内的多项体育赛事及文化活动,优先保证奥运期间的安保力量需求。法国内政部官员在26日接受采访时表示,届时每天参与安保工作的警力将达到11000人。毫无疑问,增强安保力量相应地会带来另一个问题——预算成本的增加。

六 | 近几个月来,一直有传闻法国政府要征收“奥运税”以应对举办奥运预算超支的问题,尽管总统马克龙已在近日否定了这一传闻,但依然无法打消各方对于奥运会花钱超支的担忧。巴黎奥运会的预算包括两部分——其中一部分约38.7亿欧元为巴黎奥组委的办赛费用,这笔费用的来源主要包括国际奥委会的补贴、商业赞助以及票务收入等;而另一部分大约有32亿欧元则交由一家名为奥运工程交付公司(SOLIDEO)的机构,负责奥运相关的场馆以及基础设施建设等。目前来看,由于通货膨胀带来的人力及原材料价格的上涨,场馆和基础设施建设面临的预算超支问题将更为严峻。如何保证所有场馆及基础设施按期交付,同时又将支出成本控制在合理范围之内,将考验所有相关方的智慧。对于现代奥林匹克运动来说,巴黎是一座绕不开的城市,这里是现代奥林匹克之父顾拜旦的出生地,1900年、1924年这里曾两次举办过奥运会。百年之后,奥运再回“浪漫之都”,难免让人对这届奥运会有着非同寻常的期待。巴黎奥组委希望借助这次奥运会,向全世界展现巴黎丰厚的历史文化底蕴,正如巴黎奥组委主席埃斯坦盖所说,要将奥运融入巴黎的壮丽之中,而这也是那些天马行空的方案背后的灵感来源。

七 | 理想很丰满,但现实很骨感。对于巴黎奥组委甚至法国政府来说,接下来两年的筹办工作将充满挑战。

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Published on:13:03:06

